Whitehead Member Robert Weinberg’s research featured in Boston Globe

Bob Weinberg PhotoScientists find genetic switch that may fuel breast cancer’s spread
The Boston Globe | Carolyn Y. Johnson

A new study may offer a valuable clue about how cancers become aggressive, identifying a genetic switch that in some breast cancer cells is poised to be flipped on by signals from the surrounding tumor environment. When the switch is triggered, it helps transform non-aggressive cells into cancer stem cells capable of proliferating and spreading. The switch, researchers found, is positioned differently in two types of breast cancer—one that has a greater survival rate, and one that is more prone to spread.

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